Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156820 | 0.82 | HTR6 (0.68) | HTR6PKM | |
| SCHEMBL3148482 | 0.80 | HTR6 (0.70) | HTR6 | |
| SCHEMBL14093833 | 0.79 | HTR6 (0.69) | HTR6TSHRMEN1KMT2A | |
| SCHEMBL3143762 | 0.79 | HTR6 (0.69) | HTR6TSHRMEN1KMT2A | |
| SCHEMBL3148210 | 0.79 | HTR6 (0.74) | HTR6 | |
| SCHEMBL3153469 | 0.78 | HTR6 (0.66) | HTR6 | |
| SCHEMBL3147482 | 0.78 | HTR6 (0.66) | HTR6 | |
| SCHEMBL3147199 | 0.78 | HTR6 (0.68) | HTR6TSHRMEN1KMT2A | |
| SCHEMBL3143119 | 0.78 | HTR6 (0.68) | HTR6TSHRMEN1KMT2A | |
| SCHEMBL3153497 | 0.78 | HTR6 (0.70) | HTR6CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |