Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911489 | 0.75 | GRM5 (0.33) | GRM5 | |
| SCHEMBL28596689 | 0.73 | NISCH (0.46) | CYP1A2NISCHNPC1RAB9AALDH1A1 | |
| SCHEMBL1171231 | 0.71 | NISCH (0.38) | KDM4ECYP1A2NISCHNPC1ALDH1A1 | |
| Dipyridyl SCHEMBL30434972 | 0.71 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL8655605 | 0.71 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6885910 | 0.71 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29189121 | 0.70 | KDM4E (0.70) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL18283538 | 0.69 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4400222 | 0.69 | KDM4E (0.59) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.68 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802732-B1 | HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR | ZENECA LTD (GB) | 2000-04-19 | — | — | EP | claimed |
| WO-2000011954-A1 | HERBICIDAL METHOD | AVENTIS CROPSCIENCE S.A. (FR) | 2000-03-09 | — | — | WO | claimed |
| EP-0565593-B1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO CO (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0802732-A1 | HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR | ZENECA LIMITED (GB) | 1997-10-29 | — | — | EP | claimed |
| WO-1996021357-A1 | HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR | ZENECA LIMITED (GB) | 1996-07-18 | — | — | WO | claimed |
| US-5536700-A | Herbicidal compositions comprising aryl-5-haloalkylpyrazoles and glyphosate, it's salts, diquat or paraquat | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | claimed |
| EP-0603240-A1 | SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES | MONSANTO COMPANY (US) | 1994-06-29 | — | — | EP | claimed |
| US-5281571-A | Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles | MONSANTO COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| EP-0562015-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| US-5201933-A | Haloacetamides | MONSANTO COMPANY (US) | 1993-04-13 | — | — | US | claimed |
| EP-0531271-A1 | Safening herbicidal pyrazolysulfonylureas | MONSANTO COMPANY (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1993003615-A1 | SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES | MONSANTO COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| WO-1992010098-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1992-06-25 | — | — | WO | claimed |
| EP-0480902-A1 | Safening herbicidal benzoic acid derivatives | MONSANTO COMPANY (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0436483-A2 | Safening imidazolinone herbicides | MONSANTO COMPANY (US) | 1991-07-10 | — | — | EP | claimed |
| US-20090306052-A1 | INDENYL DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | GLAXO GROUP LIMITED | 2009-12-10 | — | — | US | disclosed |
| EP-1833796-A1 | INDENYL DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | GLAXO GROUP LIMITED (GB) | 2007-09-19 | — | — | EP | disclosed |
| EP-0480902-A1 | Safening herbicidal benzoic acid derivatives | MONSANTO COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0436483-A2 | Safening imidazolinone herbicides | MONSANTO COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306052-A1 | INDENYL DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NLN, INMT, INA | KDM4E 1585/4885LMNA 1624/4885CCR1 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.