Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL874044 | 0.95 | — | — | |
| Trimethylammonium SCHEMBL874043 | 0.95 | CA1 (0.56) | CA1CA2CA9FFAR3LCK | |
| Trimethylammonium SCHEMBL28443711 | 0.95 | CA1 (0.56) | CA1CA2CA9FFAR3LCK | |
| Trimethylammonium SCHEMBL28100436 | 0.90 | — | — | |
| Trimethylammonium SCHEMBL28125697 | 0.90 | — | — | |
| Trimethylammonium SCHEMBL27780974 | 0.86 | CA1 (0.46) | CA1CA2CA9FFAR3LCK | |
| Acetic Acid SCHEMBL153379 | 0.80 | — | — | |
| Oxalic Acid SCHEMBL1579095 | 0.80 | FFAR3 (0.42) | CA1CA2CA9FFAR3LCK | |
| Acetic Acid SCHEMBL9621249 | 0.80 | FFAR3 (0.70) | CA1CA2CA9FFAR3LCK | |
| Oxalic Acid SCHEMBL1579087 | 0.80 | FFAR3 (0.42) | CA1CA2CA9FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632359-B2 | Cleaning liquid and nozzle plate cleaning method | KABUHSIKI KAISHA TOSHIBA (JP) | 2009-12-15 | — | — | US | claimed |