Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL28443711 | 1.00 | CA1 (0.56) | CA1CA2CA9FFAR3LCK | |
| Trimethylammonium SCHEMBL874044 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL4398765 | 0.95 | CA1 (0.50) | CA1CA2CA9FFAR3LCK | |
| Trimethylammonium SCHEMBL28125697 | 0.95 | — | — | |
| Trimethylammonium SCHEMBL28100436 | 0.95 | — | — | |
| Trimethylammonium SCHEMBL27780974 | 0.91 | CA1 (0.46) | CA1CA2CA9FFAR3LCK | |
| Oxalic Acid SCHEMBL1579095 | 0.84 | FFAR3 (0.42) | CA1CA2CA9FFAR3LCK | |
| Acetic Acid SCHEMBL153379 | 0.84 | — | — | |
| Acetic Acid SCHEMBL9621249 | 0.84 | FFAR3 (0.70) | CA1CA2CA9FFAR3LCK | |
| Oxalic Acid SCHEMBL1579087 | 0.84 | FFAR3 (0.42) | CA1CA2CA9FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239501-A | Method for synthesizing molecular sieve under near-neutral fluorine-free condition | 浙江大学 | 2024-06-25 | — | — | CN | claimed |
| CN-109748808-B | Preparation method of choline bicarbonate and carbonate | 济南蓬勃生物技术有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-109503395-B | Stable choline solution and preparation method thereof | 济南蓬勃生物技术有限公司 | 2021-11-16 | — | — | CN | claimed |
| EP-3600246-A1 | DRY POWDERS OF CANNABINOIDS AND METHODS FOR PREPARING DRY POWDERS | Colorado Can LLC (US) | 2020-02-05 | — | — | EP | claimed |
| CN-109748808-A | A kind of preparation method of Choline Bicarbonate and carbonate | 济南蓬勃生物技术有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-109503395-A | A kind of stable choline solution and preparation method thereof | 济南蓬勃生物技术有限公司 | 2019-03-22 | — | — | CN | claimed |
| WO-2018175637-A1 | DRY POWDERS OF CANNABINOIDS AND METHODS FOR PREPARING DRY POWDERS | COLORADO CAN LLC (US) | 2018-09-27 | — | — | WO | claimed |
| US-20180271826-A1 | DRY POWDERS OF CANNABINOIDS AND METHODS FOR PREPARING DRY POWDERS | COLORADO CAN LLC (US) | 2018-09-27 | — | — | US | claimed |
| CN-110234666-B | Vinyl alcohol polymer containing side chain olefin and method for producing same | 株式会社可乐丽 | 2025-06-03 | — | — | CN | disclosed |
| CN-119817576-A | Low residue disinfectant wipe | 阿萨达有限责任公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114728901-B | Materials and methods for differential characterization of molecular conjugates and conjugates | 詹森生物科技公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119553509-A | Preparation method of high-elasticity wear-resistant fabric | 王正文 | 2025-03-04 | — | — | CN | disclosed |
| CN-114990898-B | High-elasticity wear-resistant fabric and preparation method thereof | 上海宝鸟服饰有限公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2024137634-A1 | KIT FOR PREPARING A VOLATILE PH GRADIENT MOBILE PHASE AND METHOD FOR DETECTING AN ANALYTE | DIONEX CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20020165253-A1 | Substituted quinolinecarboxamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2002-11-07 | — | — | US | disclosed |
| WO-2002070487-A1 | SUBSTITUTED QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-1191948-A2 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORPORATION (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076556-A9 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORP (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2000076556-A2 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6053396-A | APPLYING A POLYMER SELECTED FROM THE GROUP CONSISTING OF POLYMERS HAVING OXYGEN ATOMS IN THE MAIN CHAIN AND POLYMERS CAPABLE OF BEING THERMALLY DEPOLYMERIZED, TO THE METAL SURFACE OF METAL PART TO BE WELDED, WELDING THE METAL PARTS | TOYO RIKEN CORPORATION (JP) | 2000-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165253-A1 | Substituted quinolinecarboxamides as antiviral agents | ZC3HAV1, IRF3, EIF2AK2 | CA1 2880/4885CA2 2319/4885CA9 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.