Lactitol

Lactitol

SCHEMBL4398901

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nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
TYR P14679 1/20 0.39
CD209 Q9NNX6 2/20 0.39
PTPN1 P18031 1/20 0.39
SYNJ2 O15056 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ABL1 P00519 1/20 0.38
ALPL P05186 1/20 0.38
POLB P06746 1/20 0.38
ALPI P09923 1/20 0.38
ALPG P10696 1/20 0.38
PABPC1 P11940 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maltitol SCHEMBL5914388 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL1938950 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Lactitol SCHEMBL9098934 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL14831636 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL4581977 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL1721278 1.00 PPARG (0.40) PPARGPPARDPPARAL3MBTL1MEN1
Lactitol SCHEMBL6536267 0.98 PPARG (0.39) PPARGPPARDPPARAL3MBTL1MEN1
Lactitol SCHEMBL15621059 0.98 PPARG (0.39) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL14966604 0.98 PPARG (0.39) PPARGPPARDPPARAL3MBTL1MEN1
Maltitol SCHEMBL4459148 0.98 L3MBTL1 (0.41) PPARGPPARDPPARAL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983840-B2 NON-CRYSTALLIZING SYRUPS CONTAINING SORBITOL AND THEIR USE IN CHEWING GUM WRIGLEY W M JUN CO (US) 2016-11-09 EP claimed
EP-1983840-B1 NON-CRYSTALLIZING SYRUPS CONTAINING SORBITOL AND THEIR USE IN CHEWING GUM WRIGLEY W M JUN CO (US) 2013-04-10 EP claimed
EP-1532975-B2 Process for the manufacture of free-flowing, powdery atorvastatin adsorbates HELM AG (DE) 2009-12-02 EP disclosed
EP-1532975-B1 Process for the manufacture of free-flowing, powdery atorvastatin adsorbates HELM AG (DE) 2007-02-28 EP disclosed
EP-1614412-A1 Process for the manufacture of free-flowing, powdery atorvastatin adsorbates Helm AG (DE) 2006-01-11 EP disclosed
EP-1532975-A1 Process for the manufacture of free-flowing, powdery atorvastatin adsorbates Helm AG (DE) 2005-05-25 EP disclosed
US-5846568-A Directly compressible lactitol and method XYROFIN OY (FI) 1998-12-08 US disclosed