Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476796 | 0.88 | NR3C1 (0.66) | NR3C1 | |
| SCHEMBL12663030 | 0.87 | NR3C1 (0.54) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL4399769 | 0.83 | NR3C1 (0.52) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL476767 | 0.82 | NR3C1 (0.68) | NR3C1 | |
| SCHEMBL12663031 | 0.80 | NR3C1 (0.56) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL476867 | 0.79 | NR3C1 (0.69) | NR3C1 | |
| SCHEMBL4381531 | 0.78 | NR3C1 (0.59) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL4396956 | 0.78 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL4390636 | 0.78 | NR3C1 (0.53) | NR3C1 | |
| SCHEMBL476766 | 0.74 | NR3C1 (0.66) | NR3C1PGRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |