Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410795 | 0.76 | NPC1 (0.55) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL2207537 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL4406572 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL6269910 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL54820 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL4187230 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL6269913 | 0.74 | ABCG2 (0.50) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL4404185 | 0.74 | ABCG2 (0.46) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL23625647 | 0.72 | NPC1 (0.71) | NPC1RAB9AMAPTPKMABCG2 | |
| SCHEMBL2210517 | 0.72 | NPC1 (0.77) | NPC1RAB9AMAPTPKMABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459262-A | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1995-10-17 | — | — | US | claimed |
| CN-1091734-A | The preparation method of phenylbenzamaide derivatives | RHONE POULEND AGROCHIMIE (FR) | 1994-09-07 | — | — | CN | claimed |
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | claimed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-5459262-A | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1995-10-17 | — | — | US | disclosed |
| CN-1091734-A | The preparation method of phenylbenzamaide derivatives | RHONE POULEND AGROCHIMIE (FR) | 1994-09-07 | — | — | CN | disclosed |
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | disclosed |