SCHEMBL4406572

SCHEMBL4406572

Brc1nnn(-c2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.50
HPGD P15428 3/20 0.46
KDM4E B2RXH2 3/20 0.46
NPC1 O15118 6/20 0.46
RAB9A P51151 5/20 0.46
MAPT P10636 3/20 0.45
PKM P14618 1/20 0.45
ABCB1 P08183 1/20 0.40
GRM5 P41594 1/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
MEN1 O00255 1/20 0.36
STAT1 P42224 1/20 0.36
KMT2A Q03164 1/20 0.36
P2RX7 Q99572 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA5 P30532 1/20 0.36
CHRNA4 P43681 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410795 0.76 NPC1 (0.55) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL4187230 0.74 ABCG2 (0.50) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL6269913 0.74 ABCG2 (0.50) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL6269910 0.74 ABCG2 (0.50) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL54820 0.74 ABCG2 (0.50) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL4400136 0.74 NPC1 (0.53) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL2207537 0.74 ABCG2 (0.50) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL513770 0.74 HPGD (0.57) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL23625647 0.72 NPC1 (0.71) ABCG2HPGDKDM4ENPC1RAB9A
SCHEMBL2210517 0.72 NPC1 (0.77) ABCG2KDM4ENPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106519789-A Ink for ink jet printing 松下知识产权经营株式会社 2017-03-22 CN disclosed
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed