Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401889 | 0.87 | MAPT (0.53) | MAOBMAOAACHEBCHEPIM1 | |
| SCHEMBL4427728 | 0.82 | MAPT (0.43) | MAOBMAOAACHEBCHEPIM1 | |
| SCHEMBL9049784 | 0.79 | DYRK1A (0.59) | MAOBACHEPIM1PIM2KDM4E | |
| SCHEMBL9049778 | 0.79 | DYRK1A (0.59) | MAOBACHEPIM1PIM2KDM4E | |
| SCHEMBL6660533 | 0.74 | CYP1A2 (0.53) | MAOBMAOAHPGDKDM4EMAPT | |
| SCHEMBL9047840 | 0.74 | CYP1A2 (0.53) | MAOBMAOAHPGDKDM4EMAPT | |
| SCHEMBL7399707 | 0.74 | CYP1A2 (0.53) | MAOBMAOAHPGDKDM4EMAPT | |
| SCHEMBL9049098 | 0.73 | KMT2A (0.51) | MAOBMAOAACHEPIM1PIM2 | |
| SCHEMBL9047782 | 0.73 | AKR1C3 (0.50) | MAOBMAOAACHEPIM1PIM2 | |
| SCHEMBL9049105 | 0.73 | KMT2A (0.51) | MAOBMAOAACHEPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107239-A1 | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same | ARKRAY, INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120107239-A1 | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same | ARKRAY, INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2407455-A1 | MOLECULAR PROBE PRECURSOR FOR PANCREATIC ISLET IMAGING AND USE OF SAME | Kyoto University (JP) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107239-A1 | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same | OGFRL1, OXSR1, IAPP | MAOB 1056/4885MAOA 2635/4885ACHE 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.