Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401889 | 0.89 | MAPT (0.53) | MAPTKDM4EPOLBL3MBTL1MEN1 | |
| SCHEMBL4400352 | 0.82 | MAOB (0.41) | MAPTKDM4EPOLBL3MBTL1PIM1 | |
| SCHEMBL9049778 | 0.76 | DYRK1A (0.59) | MAPTKDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL9049784 | 0.76 | DYRK1A (0.59) | MAPTKDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL11159952 | 0.73 | DYRK1A (0.68) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3681798 | 0.72 | ALDH1A1 (0.63) | MAPTMEN1KMT2ASMN1; SMN2RARB | |
| SCHEMBL4138972 | 0.72 | MAPT (0.53) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13902581 | 0.72 | MAPT (0.53) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4138976 | 0.72 | MAPT (0.53) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10629620 | 0.72 | RARB (0.64) | KDM4EL3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107239-A1 | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same | ARKRAY, INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2407455-A1 | MOLECULAR PROBE PRECURSOR FOR PANCREATIC ISLET IMAGING AND USE OF SAME | Kyoto University (JP) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107239-A1 | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same | OGFRL1, OXSR1, IAPP | MAPT 4813/4885KDM4E 4799/4885POLB 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.