Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134251 | 0.90 | MET (0.89) | MET | |
| SCHEMBL4135688 | 0.90 | MET (0.78) | MET | |
| SCHEMBL2672814 | 0.89 | MET (0.75) | MET | |
| SCHEMBL2672565 | 0.88 | MET (0.78) | MET | |
| SCHEMBL2673679 | 0.88 | MET (0.85) | MET | |
| SCHEMBL4135272 | 0.87 | MET (0.84) | MET | |
| SCHEMBL2672383 | 0.87 | MET (1.00) | MET | |
| SCHEMBL2672352 | 0.87 | MET (0.81) | MET | |
| SCHEMBL4125758 | 0.87 | MET (1.00) | MET | |
| SCHEMBL13247285 | 0.87 | MET (0.75) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173653-B2 | Pyridiazinone derivatives for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | disclosed |
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2007065518-A1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |