SCHEMBL4400729

SCHEMBL4400729

C=C(C)C(=O)OCCNC(=O)C(C)(C=C(C)C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11918224 0.93 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4397829 0.83 THRB (0.37) THRBTSHR
SCHEMBL12608193 0.81 TSHR (0.38) THRBTSHRALDH1A1
SCHEMBL15807755 0.80 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4399895 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14123276 0.77 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL12342321 0.77 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL24089176 0.76 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL838438 0.76 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17656102 0.75 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2564939-A1 Coating apparatus and coating method Fujifilm Corporation (JP) 2013-03-06 EP disclosed
EP-2447779-A1 Method for preparation of lithographic printing plate Fujifilm Corporation (JP) 2012-05-02 EP disclosed
EP-2107422-A1 Method for preparing lithographic printing plate FUJIFILM Corporation (JP) 2009-10-07 EP disclosed
EP-1520694-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2008-12-10 EP disclosed
EP-1739482-A1 IMAGE-FORMING PROCESS, LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHY PROCESS FUJI PHOTO FILM CO., LTD. (JP) 2007-01-03 EP disclosed