SCHEMBL4400877

SCHEMBL4400877

CCN(CC)c1ccc(C(C)(C)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
TSHR P16473 3/20 0.54
CYP3A4 P08684 2/20 0.54
GFER P55789 2/20 0.54
PSMD14 O00487 1/20 0.54
MAPK1 P28482 1/20 0.54
RECQL P46063 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH3A1 P30838 1/20 0.50
ALDH1A3 P47895 1/20 0.50
CNR2 P34972 2/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 3/20 0.42
ESR1 P03372 1/20 0.42
AR P10275 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27833273 0.90 ESRRG (0.61) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL12551466 0.90 ALDH1A1 (0.45) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL15489468 0.88 MAPT (0.51) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL6278267 0.86 ALDH1A1 (0.54) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL5494992 0.86 ALDH1A1 (0.54) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL12601922 0.84 NR1H2 (0.43) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL13211689 0.83 ALDH1A1 (0.56) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL15984367 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL1735497 0.82 ALDH1A1 (0.74) ALDH1A1L3MBTL1TSHRCYP3A4GFER
SCHEMBL15489501 0.80 GSK3B (0.46) ALDH1A1L3MBTL1TSHRCYP3A4GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed