Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 4/20 | 0.30 |
| ▸ | MMP7 | P09237 | 3/20 | 0.30 |
| ▸ | MMP12 | P39900 | 3/20 | 0.30 |
| ▸ | MMP13 | P45452 | 3/20 | 0.30 |
| ▸ | ACE | P12821 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233661 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL11245171 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL11242337 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL11240071 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL11249146 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL11237057 | 0.93 | CSNK1E (0.38) | CNR2ALDH1A1MEN1KMT2ACSNK1E | |
| SCHEMBL4402575 | 0.89 | AOC3 (0.32) | SMN1; SMN2 | |
| SCHEMBL9492601 | 0.85 | CNR2 (0.33) | PCSK9CNR2POLBALDH1A1KDM4E | |
| SCHEMBL11789090 | 0.83 | CYP3A4 (0.33) | — | |
| SCHEMBL10343332 | 0.83 | CYP3A4 (0.33) | POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075244-A | Polyketone resin composition having excellent wear resistance | 株式会社晓星 | 2017-08-18 | — | — | CN | disclosed |
| CN-106661322-A | Polyketone resin composition having excellent oil resistance | 株式会社晓星 | 2017-05-10 | — | — | CN | disclosed |
| CN-106604950-A | Polyketone resin composition having outstanding water resistance | 株式会社晓星 | 2017-04-26 | — | — | CN | disclosed |
| US-7632827-B2 | Antitumor agents; cytotoxic toward cells in vivo, in vitro | THE UNIVERSITY OF HONG KONG (HK) | 2009-12-15 | — | — | US | disclosed |
| US-20080166429-A1 | ANTI-CANCER PHOSPHINE CONTAINING [AuIIIm(CNC)mL]n+ COMPLEXES AND DERIVATIVES THEREOF AND METHODS FOR TREATING CANCER USING SUCH COMPOSITIONS | THE UNIVERSITY OF HONG KONG | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166429-A1 | ANTI-CANCER PHOSPHINE CONTAINING [AuIIIm(CNC)mL]n+ COMPLEXES AND DERIVATIVES THEREOF AND METHODS FOR TREATING CANCER USING SUCH COMPOSITIONS | NCL, NPM1, MCL1 | PCSK9 4615/4885CNR2 3699/4885POLB 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.