Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237057 | 1.00 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL11249146 | 1.00 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL11242337 | 1.00 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL11245171 | 1.00 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL11233661 | 1.00 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL4401377 | 0.93 | PCSK9 (0.33) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL4402575 | 0.86 | AOC3 (0.32) | — | |
| SCHEMBL14148643 | 0.83 | CSNK1E (0.38) | CSNK1EALDH1A1CNR2MEN1KMT2A | |
| SCHEMBL11789090 | 0.81 | CYP3A4 (0.33) | — | |
| SCHEMBL27262505 | 0.81 | CSNK1E (0.51) | CSNK1ECNR2MEN1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |