Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933852 | 0.98 | TSHR (0.47) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL7933198 | 0.98 | TSHR (0.47) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL56994 | 0.94 | TSHR (0.50) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| Ammonia Solution, Strong SCHEMBL1579461 | 0.92 | TSHR (0.48) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL11670561 | 0.91 | L3MBTL1 (0.44) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL1447146 | 0.88 | TSHR (0.44) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL989008 | 0.87 | PIK3CD (0.52) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL19514132 | 0.87 | PIK3CD (0.52) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL31632694 | 0.87 | PIK3CD (0.52) | TSHRADRA1BADRA1APIK3CDKMT2A | |
| SCHEMBL5697292 | 0.87 | PIK3CD (0.52) | TSHRADRA1BADRA1APIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124274-B1 | ELECTRON BEAM SENSITIVE MIXTURE RESIST | GAF CORPORATION (US) | 1988-06-22 | — | — | EP | claimed |
| EP-0088977-B1 | ELECTRON BEAM SENSITIVE RESIST | GAF CORPORATION (US) | 1988-06-01 | — | — | EP | claimed |
| EP-0126652-B1 | ELECTRON BEAM SENSITIVE MIXTURE RESIST | GAF CORPORATION (US) | 1987-04-22 | — | — | EP | claimed |
| EP-0126652-A1 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-28 | — | — | EP | claimed |
| EP-0124274-A2 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-07 | — | — | EP | claimed |
| US-4448875-A | HALF-ESTER OR -AMIDE OF ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER | GAF CORPORATION (US) | 1984-05-15 | — | — | US | claimed |
| EP-0088977-A2 | Electron beam sensitive resist | GAF CORPORATION (US) | 1983-09-21 | — | — | EP | claimed |
| US-4375398-A | CROSSLINKING, VINYL ETHER | GAF CORPORATION (US) | 1983-03-01 | — | — | US | claimed |
| US-4022624-A | N-(AMINOALKYL)-LACTAM | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-10 | — | — | US | claimed |
| US-10729701-B2 | Compounds that are analogs of squalamine, used as antibacterial agents | VIRBAC (FR) | 2020-08-04 | — | — | US | disclosed |
| EP-3268008-B1 | COMPOUNDS THAT ARE ANALOGS OF SQUALAMINE, USED AS ANTIBACTERIAL AGENTS | VIRBAC (FR) | 2020-02-12 | — | — | EP | disclosed |
| US-20180042942-A1 | Compounds that are Analogs of Squalamine, Used as Antibacterial Agents | VIRBAC (FR) | 2018-02-15 | — | — | US | disclosed |
| US-20180042942-A1 | Compounds that are Analogs of Squalamine, Used as Antibacterial Agents | VIRBAC (FR) | 2018-02-15 | — | — | US | disclosed |
| WO-2016142922-A1 | COMPOUNDS THAT ARE ANALOGS OF SQUALAMINE, USED AS ANTIBACTERIAL AGENTS | VIRBAC (FR) | 2016-09-15 | — | — | WO | disclosed |
| EP-0124274-A2 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4448876-A | Electron beam sensitive resist | GAF CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4448875-A | HALF-ESTER OR -AMIDE OF ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER | GAF CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| EP-0088977-A2 | Electron beam sensitive resist | GAF CORPORATION (US) | 1983-09-21 | — | — | EP | disclosed |
| US-4375398-A | CROSSLINKING, VINYL ETHER | GAF CORPORATION (US) | 1983-03-01 | — | — | US | disclosed |
| US-4022624-A | N-(AMINOALKYL)-LACTAM | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042942-A1 | Compounds that are Analogs of Squalamine, Used as Antibacterial Agents | SQLE, MTX1, SPIN1 | TSHR 4539/4885ADRA1B 2346/4885ADRA1A 1845/4885 |
| US-10729701-B2 | Compounds that are analogs of squalamine, used as antibacterial agents | SQLE, MTX1, SPIN1 | TSHR 4539/4885ADRA1B 2346/4885ADRA1A 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.