⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819437 | 0.80 | MAPT (0.32) | — | |
| SCHEMBL2423602 | 0.80 | — | — | |
| SCHEMBL2186947 | 0.76 | — | — | |
| SCHEMBL454946 | 0.76 | — | — | |
| SCHEMBL9189179 | 0.76 | — | — | |
| SCHEMBL980439 | 0.76 | — | — | |
| SCHEMBL16585731 | 0.76 | — | — | |
| SCHEMBL1276119 | 0.76 | — | — | |
| SCHEMBL97062 | 0.76 | — | — | |
| SCHEMBL7309385 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307173-B1 | Pyrroline chromophores | UNIVERSITY OF WASHINGTON (US) | 2007-12-11 | — | — | US | claimed |
| CN-1289475-C | N-substituted aminotetralins as ligands for the neuropeptide YY5 receptor useful in the treatment of obesity and other disorders | ORTHO MCNEIL PHARM INC (US) | 2006-12-13 | — | — | CN | claimed |
| CN-1298386-A | N-substituted aminotetralins as ligands for the neuropeptide YY5 receptor useful in the treatment of obesity and other disorders | ORTHO MCNEIL PHARM INC (US) | 2001-06-06 | — | — | CN | claimed |
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | claimed |
| WO-1996009046-A1 | 5α-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | claimed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | claimed |
| EP-2793900-B1 | ALPHA-AMINO BORONIC ACID DERIVATIVES, SELECTIVE IMMUNOPROTEASOME INHIBITORS | ARES TRADING SA (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-9688702-B2 | Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors | ARES TRADING (CH) | 2017-06-27 | — | — | US | disclosed |
| US-9511378-B2 | Collector compositions and methods for making and using same | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-9457357-B2 | Mixed collector compositions | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2016-10-04 | — | — | US | disclosed |
| WO-2016059412-A1 | 6,7-HETEROCYCLIC FUSED 5H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES AND THEIR USE AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) AND/OR TRYPTOPHAN 2,3-DIOXYGENASE (TD02) MODULATORS | REDX PHARMA PLC (GB) | 2016-04-21 | — | — | WO | disclosed |
| WO-2016051181-A1 | 4H-IMIDAZO[1,5-A]INDOLE DERIVATIVES AND THEIR USE AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) AND/OR TRYPTOPHAN 2,3-DIOXYGENASE (TD02) MODULATORS | REDX PHARMA PLC (GB) | 2016-04-07 | — | — | WO | disclosed |
| US-9150519-B2 | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis | MERCK SERONO SA (CH) | 2015-10-06 | — | — | US | disclosed |
| US-5081240-A | PROCESS FOR THE PREPARATION OF BENZOTHIAZEPIN-ONE DERIVATIVES | SANOFI (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0115394-B1 | PHENOTHIAZONE DERIVATIVES AND ANALOGS | MERCK FROSST CANADA INC. (CA) | 1989-06-28 | — | — | EP | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| EP-0155623-A2 | Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition | MERCK & CO. INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0115394-A2 | Phenothiazone derivatives and analogs | MERCK FROSST CANADA INC. (CA) | 1984-08-08 | — | — | EP | disclosed |
| EP-0002938-B1 | NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |