⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819437 | 0.78 | MAPT (0.32) | — | |
| SCHEMBL2423602 | 0.78 | — | — | |
| SCHEMBL440187 | 0.76 | — | — | |
| SCHEMBL980439 | 0.74 | — | — | |
| SCHEMBL9189179 | 0.74 | — | — | |
| SCHEMBL2186947 | 0.74 | — | — | |
| SCHEMBL1276119 | 0.74 | — | — | |
| SCHEMBL97062 | 0.74 | — | — | |
| SCHEMBL16585731 | 0.74 | — | — | |
| SCHEMBL7309385 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149234-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| WO-2023090822-A1 | NOVEL CANNABICHROMENIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR IMPROVING COGNITIVE FUNCTION | 강원대학교 산학협력단 | 2023-05-25 | — | — | WO | claimed |
| EP-1846387-A2 | BIS-(COUMARIN) COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2007-10-24 | — | — | EP | claimed |
| WO-2006111858-A2 | BIS-(COUMARIN) COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2006-10-26 | — | — | WO | claimed |
| EP-1109787-B1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | ASTRAZENECA AB (SE) | 2006-05-17 | — | — | EP | claimed |
| WO-2005002514-A2 | COMPOUNDS HAVING INHIBITIBE ACTIVITY OF PHOSPHATIDYLINOSITOL 3-KINASE AND METHODS OF USE THEREOF | ECHELON BIOSCIENCES INCORPORATED (US) | 2005-01-13 | — | — | WO | claimed |
| US-6734184-B1 | Arylpiperazines and their use as metalloproteinase inhibiting agents (MMP) | ASTRAZENECA AB (SE) | 2004-05-11 | — | — | US | claimed |
| US-20030100548-A1 | Arylpiperazines and their use as metallaproteinase inhibiting agents (mmp) | ASTRAZENECA AB (SE) | 2003-05-29 | — | — | US | claimed |
| EP-1274697-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | AstraZeneca AB (SE) | 2003-01-15 | — | — | EP | claimed |
| WO-2001062750-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | claimed |
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| WO-2024149234-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023090822-A1 | NOVEL CANNABICHROMENIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR IMPROVING COGNITIVE FUNCTION | 강원대학교 산학협력단 | 2023-05-25 | — | — | WO | disclosed |
| CN-110199401-B | Organic solar cell | 株式会社LG化学 | 2023-05-12 | — | — | CN | disclosed |
| WO-2016046779-A1 | ZINC POLYAZAMACROCYCLIC COMPLEXES | ENI S.P.A. (IT) | 2016-03-31 | — | — | WO | disclosed |
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |
| EP-0263352-A1 | Imidazo-benzoxazinones, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-04-13 | — | — | EP | disclosed |
| EP-0172031-A1 | Novel sulfenylated acylhydrazones, compositions containing them, methods of making them and their use | ROHM AND HAAS COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4361563-A | CARDIOTONIC, ANTITHROMBOTIC | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-11-30 | — | — | US | disclosed |
| EP-0008391-A1 | Benzimidazoles, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1980-03-05 | — | — | EP | disclosed |