⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107556 | 0.73 | MAPT (0.44) | — | |
| SCHEMBL1712836 | 0.73 | NR1H2 (0.40) | — | |
| SCHEMBL8985697 | 0.71 | — | — | |
| SCHEMBL1149898 | 0.69 | — | — | |
| SCHEMBL6926292 | 0.69 | — | — | |
| SCHEMBL19561417 | 0.69 | CYP3A4 (0.30) | — | |
| SCHEMBL76856 | 0.69 | — | — | |
| SCHEMBL10534201 | 0.69 | — | — | |
| SCHEMBL1359543 | 0.69 | — | — | |
| SCHEMBL714545 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092037-A1 | Glucopyranosyl sulfates as modulators of the complement system | AMERICAN CYANAMID COMPANY (US) | 1983-10-26 | — | — | EP | claimed |
| EP-2793900-B1 | ALPHA-AMINO BORONIC ACID DERIVATIVES, SELECTIVE IMMUNOPROTEASOME INHIBITORS | ARES TRADING SA (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-9688702-B2 | Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors | ARES TRADING (CH) | 2017-06-27 | — | — | US | disclosed |
| US-9150519-B2 | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis | MERCK SERONO SA (CH) | 2015-10-06 | — | — | US | disclosed |
| US-20150274657-A1 | PYRROLIDINES | MERCK PATENT GMBH (DE) | 2015-10-01 | — | — | US | disclosed |
| EP-2903966-A1 | PYRROLIDINES | Merck Patent GmbH (DE) | 2015-08-12 | — | — | EP | disclosed |
| US-20140364396-A1 | Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors | ARES TRADING SA (CH) | 2014-12-11 | — | — | US | disclosed |
| US-8889668-B2 | Oxadiazole diaryl compounds | MERCK SERONO SA (CH) | 2014-11-18 | — | — | US | disclosed |
| US-8815919-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2014-08-26 | — | — | US | disclosed |
| US-8802704-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2014-08-12 | — | — | US | disclosed |
| US-5013831-A | Medical diagnosis, therapy | ENZO BIOCHEM, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-5002885-A | Detectable molecules, method preparation and use | ENZO BIOCHEM, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4952685-A | CARRYING A METAL COMPLEXING OR BIOTIN DETECTABLE GROUPS; NUCLEOTIDES | ENZO BIOCHEM, INC. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4943523-A | METAL CHELATING GROUPS OR BIOTIN ATTACHED TO POLYSACCHARIDES, POLYPEPTIDES, POLYNUCLEOTIDES OR SYNTHETIC POLYMERS; IMMUNOASSAY IMAGING | ENZO BIOCHEM, INC. (US) | 1990-07-24 | — | — | US | disclosed |
| US-4849208-A | Detectable molecules, method of preparation and use | ENZO BIOCHEM, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4849505-A | Detectable molecules, method of preparation and use | ENZO BIOCHEM, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4843122-A | COUPLING AGENT BETWEEN BIOPOLYMER AND CHELATE AGENT OR BIOTIN | ENZO BIOCHEM, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0098252-B1 | NEW AND NOVEL GLYCOSIDES, GLYCOCONJUGATES AND PROCESSES FOR THEIR PREPARATION | BIOCARB AB (SE) | 1989-06-07 | — | — | EP | disclosed |
| US-4707440-A | BIOPOLYMER LINKED TO A CHELATING AGENT BASED ON AN O-CYCLOHEXADIAMINEDIACETIC ACID | ENZO BIOCHEM, INC. (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0154788-A2 | Detectable molecules, method of preparation and use | ENZO BIOCHEM, INC. (US) | 1985-09-18 | — | — | EP | disclosed |