SCHEMBL1712836

SCHEMBL1712836

[c]1ccc(Sc2cc[c]cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.40
DDAH1 O94760 1/20 0.40
NOS1 P29475 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
MAOA P21397 4/20 0.35
MAOB P27338 4/20 0.35
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237662 0.88 MAOA (0.50) NR1H2MAPK1MAOAMAOBHPGD
SCHEMBL5023998 0.86 MAOA (0.54) NR1H2CYP3A4TSHRMAPK1MAOA
SCHEMBL13837350 0.86 NR1H2 (0.38) NR1H2DDAH1NOS1CYP3A4TSHR
SCHEMBL4580401 0.84 MAOA (0.56) NR1H2CYP3A4TSHRMAPK1MAOA
SCHEMBL3163844 0.84 MLYCD (0.44) NR1H2CYP3A4TSHRMAPK1LMNA
SCHEMBL4098191 0.84 NR1H2 (0.70) NR1H2CYP3A4TSHRMAPK1MAOA
SCHEMBL5687695 0.84 MAOA (0.56) NR1H2CYP3A4TSHRMAPK1MAOA
SCHEMBL4612503 0.84 DDAH1 (0.70) NR1H2DDAH1NOS1CYP3A4TSHR
SCHEMBL5685447 0.84 MEN1 (0.40) NR1H2CYP3A4TSHRMAPK1MAOA
SCHEMBL4615103 0.84 CYP3A4 (0.70) NR1H2CYP3A4TSHRMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7488517-B2 Method of producing porous nitrile rubber coated indoor athletic socks WHANG BRIAN 2009-02-10 US claimed
EP-1722633-A2 NEW INSECTICIDE COMPOSITION AND ITS USE, NAMELY FOR IMPREGNATION OF MOSQUITO NETS Institut de Recherche pour le Développement ( IRD) (FR) 2006-11-22 EP claimed
EP-1651360-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME Valspar Sourcing, Inc. (US) 2006-05-03 EP claimed
WO-2005079577-A2 NOVEL INSECTICIDE COMPOSITION AND USE THEREOF PARTICULARLY FOR IMPREGNATING MOSQUITO NETS, FLY SCREENS AND THE LIKE INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2005-09-01 WO claimed
WO-2005011880-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME VALSPAR SOURCING, INC. (US) 2005-02-10 WO claimed
US-6200961-B1 FREE OF VOLATILE ORGANIC COMPOUNDS, STABILITY; FOR CONTROLLING INSECTS AQUATROLS CORPORATION OF AMERICA, INC. 2001-03-13 US claimed
EP-1043927-A1 AGROCHEMICAL EMULSIFIABLE CONCENTRATES Aquatrols Holding Co., Inc. (US) 2000-10-18 EP claimed
WO-1999033340-A1 AGROCHEMICAL EMULSIFIABLE CONCENTRATES AQUATROLS HOLDING CO., INC. (US) 1999-07-08 WO claimed
EP-0106023-B1 END-CAPPED POLYARYLENE POLYETHERS, ARTICLES MADE THEREFROM AND PROCESS FOR PREPARING SUCH POLYARYLENE POLYETHERS AMOCO CORPORATION (US) 1988-03-30 EP claimed
EP-0106023-A2 End-capped polyarylene polyethers, articles made therefrom and process for preparing such polyarylene polyethers AMOCO CORPORATION (US) 1984-04-25 EP claimed
US-3991014-A Polyesters of derivatives of hydroquinone and bis(carboxyphenyl)ether E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 US claimed
US-12018164-B2 Printing substance for coating glass surfaces VIBRANTZ GMBH (DE) 2024-06-25 US disclosed
CN-113302222-B Cationically curable compositions and methods of joining, casting and coating substrates using the same 德路工业胶粘剂有限两合公司 2023-09-15 CN disclosed
CN-112654685-B Radical adhesive composition, adhesive layer, polarizing plate and image display device 株式会社LG化学 2022-12-23 CN disclosed
US-20220403196-A1 Printing Substance For Coating Glass Surfaces VIBRANTZ GMBH (DE) 2022-12-22 US disclosed
US-5023380-A Monomer for thermoplastic resin THE DOW CHEMICAL COMPANY (US) 1991-06-11 US disclosed
EP-0106023-B1 END-CAPPED POLYARYLENE POLYETHERS, ARTICLES MADE THEREFROM AND PROCESS FOR PREPARING SUCH POLYARYLENE POLYETHERS AMOCO CORPORATION (US) 1988-03-30 EP disclosed
US-4145544-A TRIMERIZING AROMATIC ISOCYANATE AND AN UNSATURATED SOLVENT, REACTING WITH ALCOHOL ICI AMERICAS INC. (US) 1979-03-20 US disclosed
US-4041151-A CONTROLLING SIPHONAPTERA ON DOGS AND CATS, POLYVINYL CHLORIDE COLLAR AMERICAN CYANAMID COMPANY (US) 1977-08-09 US disclosed
US-3991014-A Polyesters of derivatives of hydroquinone and bis(carboxyphenyl)ether E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 US disclosed