Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29037393 | 1.00 | SOAT1 (0.63) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL27297917 | 1.00 | SOAT1 (0.63) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28111051 | 1.00 | SOAT1 (0.63) | SOAT1MEN1KMT2AFAAHTP53 | |
| Phosphoric Acid SCHEMBL28788052 | 1.00 | SOAT1 (0.63) | SOAT1MEN1KMT2AFAAHTP53 | |
| Phosphoric Acid SCHEMBL27519947 | 0.98 | SOAT1 (0.59) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL218242 | 0.90 | SOAT1 (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL27869 | 0.90 | SOAT1 (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL42192 | 0.90 | SOAT1 (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL22319678 | 0.90 | SOAT1 (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL104521 | 0.90 | SOAT1 (0.74) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114410129-B | Nanometer calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-114410129-A | Nano calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-118578804-A | Thermosensitive recording material | 乐凯医疗科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-117467285-A | Preparation method of nano calcium carbonate capable of improving ageing resistance of photovoltaic sealant | 广西华纳新材料股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114410129-B | Nanometer calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-114410129-B | Nanometer calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116023803-A | Modification method of nano calcium carbonate special for sealant | 广西平果市润丰钙新材料科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-114410129-A | Nano calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410129-A | Nano calcium carbonate for double-component MS sealant and surface treatment method thereof | 安徽省宣城市华纳新材料科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-8481075-B2 | Preparation and application of biodegradable-material-made microsphere vascular embolus containing liposome-encapsulated cytokines | BEIJING SHENGYIYAO SCIENCE & TECHNOLOGY DEVELOPMENT CO. LTD. (CN) | 2013-07-09 | — | — | US | disclosed |
| US-20090155344-A1 | PREPARATION AND APPLICATION OF BIODEGRADABLE-MATERIAL-MADE MICROSPHERE VASCULAR EMBOLUS CONTAINING LIPOSOME-ENCAPSULATED CYTOKINES | BEIJING SHENGYIYAO SCIENCE & TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2009-06-18 | — | — | US | disclosed |
| CN-1382808-A | Process for preparing greasing agent | CHENGDU ORGANIC CHEM INST (CN) | 2002-12-04 | — | — | CN | disclosed |
| CN-1081912-C | Conditioning shampoos containing polyvalent metal cations | PROCTER & GAMBLE (US) | 2002-04-03 | — | — | CN | disclosed |
| CN-1038015-C | Shampoo compositions with silicone and cationic surfactant conditioning agents | PROCTER & GAMBLE (US) | 1998-04-15 | — | — | CN | disclosed |
| CN-1129902-A | Conditioning shampoos containing polyvalent metal cations | PROCTER & GAMBLE (US) | 1996-08-28 | — | — | CN | disclosed |
| CN-1062836-A | Shampoo composite with silicone and cationic surfactant conditioning agents | PROCTER & GAMBLE (US) | 1992-07-22 | — | — | CN | disclosed |