Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | CA6 | P23280 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | TYR | P14679 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | KMO | O15229 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5494023 | 1.00 | CA12 (0.72) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL28317800 | 1.00 | CA12 (0.72) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL9634104 | 1.00 | CA12 (0.72) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL18529299 | 0.96 | CA12 (0.78) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28884852 | 0.96 | CA12 (0.78) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL4957668 | 0.96 | CA12 (0.78) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL11040369 | 0.93 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28378402 | 0.93 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL8766630 | 0.93 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL28751510 | 0.92 | CA12 (0.62) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884822-B2 | Low temperature foamable polycarbonate composition and articles thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-01-30 | — | — | US | claimed |
| US-20240026150-A1 | Thermoplastic Compositions Including Natural Fiber Having Good Mechanical Properties and Good Dielectric Properties | SHPP GLOBAL TECH BV (NL) | 2024-01-25 | — | — | US | claimed |
| EP-3798263-B1 | LOW TEMPERATURE FOAMABLE POLYCARBONATE COMPOSITION AND ARTICLES THEREOF | SHPP GLOBAL TECH BV (NL) | 2024-01-24 | — | — | EP | claimed |
| EP-3919569-B1 | THERMOPLASTIC COMPOSITIONS INCLUDING NATURAL FIBER HAVING GOOD MECHANICAL PROPERTIES AND GOOD DIELECTRIC PROPERTIES | SHPP GLOBAL TECH BV (NL) | 2023-07-26 | — | — | EP | claimed |
| US-20230193019-A1 | Thermoplastic Compositions Including Natural Fiber Having Good Mechanical Properties and Good Dielectric Properties | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-06-22 | — | — | US | claimed |
| CN-116134097-A | Thermoplastic composition comprising natural fibers with good mechanical properties and good dielectric properties | 高新特殊工程塑料全球技术有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115335429-A | Low temperature foamable flame retardant polycarbonate compositions | 高新特殊工程塑料全球技术有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-112041393-B | Improved flame retardant compositions | 高新特殊工程塑料全球技术有限公司 | 2022-08-16 | — | — | CN | claimed |
| EP-3919569-A1 | THERMOPLASTIC COMPOSITIONS INCLUDING NATURAL FIBER HAVING GOOD MECHANICAL PROPERTIES AND GOOD DIELECTRIC PROPERTIES | SHPP Global Technologies B.V. (NL) | 2021-12-08 | — | — | EP | claimed |
| US-11124650-B2 | Flame retardant compositions | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2021-09-21 | — | — | US | claimed |
| CN-107922616-B | Thermoplastic composition with balanced chemical resistance and impact properties | 沙特基础工业全球技术有限公司 | 2020-05-29 | — | — | CN | claimed |
| WO-2020079565-A1 | CONTINUOUS FIBER REINFORCED COMPOSITE PREPREG FORMED OF FLAME RETARDANT POLYESTER | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-04-23 | — | — | WO | claimed |
| CN-110922733-A | Polycarbonate articles and methods of making the same | 沙特基础工业全球技术有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-106457782-B | Method for additive manufacturing using thermoplastic material having a selected melt index | 沙特基础工业全球技术有限公司 | 2019-12-10 | — | — | CN | claimed |
| EP-3540011-A1 | IMPROVED FLAME RETARDANT COMPOSITIONS | SABIC Global Technologies B.V. (NL) | 2019-09-18 | — | — | EP | claimed |
| EP-3458493-A1 | THERMOPLASTIC COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM | SABIC Global Technologies B.V. (NL) | 2019-03-27 | — | — | EP | claimed |
| WO-2017200829-A1 | THERMOPLASTIC COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-11-23 | — | — | WO | claimed |
| US-20170144368-A1 | PROCESS FOR ADDITIVE MANUFACTURING USING THERMOPLASTIC MATERIALS HAVING SELECTED MELT INDEXES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-05-25 | — | — | US | claimed |
| EP-3154785-A1 | PROCESS FOR ADDITIVE MANUFACTURING USING THERMOPLASTIC MATERIALS HAVING SELECTED MELT INDEXES | SABIC Global Technologies B.V. (NL) | 2017-04-19 | — | — | EP | claimed |
| WO-2015195527-A1 | PROCESS FOR ADDITIVE MANUFACTURING USING THERMOPLASTIC MATERIALS HAVING SELECTED MELT INDEXES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-12-23 | — | — | WO | claimed |