Terephthalic Acid

Terephthalic Acid

SCHEMBL5494023

O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1cccc(C(=O)O)c1.O=C(O)c1ccccc1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.72
CA1 P00915 2/20 0.72
CA2 P00918 2/20 0.72
CA6 P23280 2/20 0.72
CA9 Q16790 2/20 0.72
CA3 P07451 1/20 0.62
TYR P14679 1/20 0.62
DRD1 P21728 1/20 0.62
CA4 P22748 1/20 0.62
CA5A P35218 1/20 0.62
CA7 P43166 1/20 0.62
CA14 Q9ULX7 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
TSHR P16473 2/20 0.61
DAO P14920 1/20 0.61
NAPRT Q6XQN6 1/20 0.61
CES2 O00748 2/20 0.58
SRD5A2 P31213 2/20 0.58
CES1 P23141 1/20 0.58
KMO O15229 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL440232 1.00 CA12 (0.72) CA12CA1CA2CA6CA9
Terephthalic Acid SCHEMBL28317800 1.00 CA12 (0.72) CA12CA1CA2CA6CA9
Terephthalic Acid SCHEMBL9634104 1.00 CA12 (0.72) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL18529299 0.96 CA12 (0.78) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28884852 0.96 CA12 (0.78) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL4957668 0.96 CA12 (0.78) CA12CA1CA2CA6CA9
Terephthalic Acid SCHEMBL11040369 0.93 CA12 (0.73) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28378402 0.93 CA12 (0.73) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL8766630 0.93 CA12 (0.73) CA12CA1CA2CA6CA9
Terephthalic Acid SCHEMBL28751510 0.92 CA12 (0.62) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815876-B1 Instrument sterilization container formed of a liquid crystal polymer ETHICON INC (US) 2003-10-08 EP claimed
US-6379631-B1 FOR MEDICAL EQUIPMENT; POLYESTERS SUCH AS POLYBENZOATE NAPHTHALATE, POLYBENZOATE TEREPHTHALATE BISPHENOL ISOPHTHALATE; HIGH STRENGTH JOHNSON & JOHNSON MEDICAL, INC. 2002-04-30 US claimed
EP-0815876-A2 Instrument sterilization container formed of a liquid crystal polymer JOHNSON & JOHNSON MEDICAL, INC. (US) 1998-01-07 EP claimed
WO-2015107095-A1 POLYMER FILM CEDAR ADVANCED TECHNOLOGY GROUP LTD. (CH) 2015-07-23 WO disclosed
US-7300637-B2 Sterilization container kit ETHICON, INC. (US) 2007-11-27 US disclosed
US-6759017-B2 STERILIZATION ENCLOSURES SEPARATED VERTICALLY BY A STACKING DEVICE THAT ALLOWS DIFFUSION BETWEEN THE ENCLOSURES AND INTO THE ENCLOSURES THROUGH THEIR UPPER AND LOWER FACING PORTIONS. ETHICON, INC. 2004-07-06 US disclosed
US-6692693-B2 A STERILIZATION CONTAINER FOR STERILIZING, STORING AND TRANSPORTING MEDICAL INSTRUMENTS IS FORMED OF A LIQUID CRYSTAL POLYMER, SUCH AS AN AROMATIC POLYESTER ETHICON, INC. 2004-02-17 US disclosed
US-6692693-B2 A STERILIZATION CONTAINER FOR STERILIZING, STORING AND TRANSPORTING MEDICAL INSTRUMENTS IS FORMED OF A LIQUID CRYSTAL POLYMER, SUCH AS AN AROMATIC POLYESTER ETHICON, INC. 2004-02-17 US disclosed
CN-1135118-C Container of LCD polymer for apparatus sterilizing �Ϳ���ҽҩ��˾ 2004-01-21 CN disclosed
US-20030211023-A1 Instrument sterilization container having improved diffusion ETHICON, INC. 2003-11-13 US disclosed
EP-0815876-B1 Instrument sterilization container formed of a liquid crystal polymer ETHICON INC (US) 2003-10-08 EP disclosed
US-6379631-B1 FOR MEDICAL EQUIPMENT; POLYESTERS SUCH AS POLYBENZOATE NAPHTHALATE, POLYBENZOATE TEREPHTHALATE BISPHENOL ISOPHTHALATE; HIGH STRENGTH JOHNSON & JOHNSON MEDICAL, INC. 2002-04-30 US disclosed
US-6264902-B1 STERILIZATION, TRANSPORTATING, STORAGE; RECESSED LATCH JOHNSON & JOHNSON MEDICAL, INC. 2001-07-24 US disclosed
US-6193932-B1 Sterilization container and instrument holder therefor ETHICON, INC. 2001-02-27 US disclosed
EP-0815876-A3 Instrument sterilization container formed of a liquid crystal polymer JOHNSON & JOHNSON MEDICAL, INC. (US) 1999-12-15 EP disclosed
CN-1182624-A Container of LCD polymer for apparatus sterilizing JOHNSON & JOHNSON MEDICAL (US) 1998-05-27 CN disclosed
EP-0815874-A2 Instrument sterilization container having improved drainage and support for an instrument mat JOHNSON & JOHNSON MEDICAL, INC. (US) 1998-01-07 EP disclosed
EP-0815875-A2 Instrument sterilization container having an improved latching mechanism JOHNSON & JOHNSON MEDICAL, INC. (US) 1998-01-07 EP disclosed
EP-0815876-A2 Instrument sterilization container formed of a liquid crystal polymer JOHNSON & JOHNSON MEDICAL, INC. (US) 1998-01-07 EP disclosed
EP-0815876-A2 Instrument sterilization container formed of a liquid crystal polymer JOHNSON & JOHNSON MEDICAL, INC. (US) 1998-01-07 EP disclosed