Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 6/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280260 | 0.88 | VDR (0.62) | VDR | |
| SCHEMBL4412728 | 0.83 | VDR (0.44) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL6155760 | 0.81 | VDR (0.42) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL3280131 | 0.79 | VDR (1.00) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL3280121 | 0.79 | VDR (1.00) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL3280127 | 0.79 | VDR (1.00) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL6564851 | 0.79 | VDR (0.42) | VDR | |
| SCHEMBL3280129 | 0.78 | VDR (0.72) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL3279968 | 0.76 | VDR (0.73) | VDRMAOBF2NR4A2NR4A1 | |
| SCHEMBL3279689 | 0.76 | VDR (0.73) | VDRMAOBF2NR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |