Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GSK3A | P49840 | 3/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12535737 | 0.90 | GSK3B (0.39) | KCNJ6KCNJ3MAPK14RAF1GSK3B | |
| SCHEMBL4442622 | 0.89 | HDAC4 (0.34) | MAPK14F10GSK3BMAPTGSK3A | |
| SCHEMBL4401609 | 0.88 | MAPK14 (0.38) | MAPK14RAF1F10GSK3BMAPT | |
| SCHEMBL2680635 | 0.85 | F10 (0.43) | KCNJ6KCNJ3MAPK14F10MCHR1 | |
| SCHEMBL2680858 | 0.82 | MEN1 (0.38) | MAPK14F10GSK3BMAPTGSK3A | |
| SCHEMBL12535751 | 0.81 | GSK3B (0.40) | KCNJ6KCNJ3MAPK14RAF1GSK3B | |
| SCHEMBL1726708 | 0.80 | GSK3B (0.39) | MAPK14RAF1GSK3BMAPTGSK3A | |
| SCHEMBL9884611 | 0.79 | KCNJ6 (0.40) | KCNJ6KCNJ3MAPK14RAF1GSK3B | |
| SCHEMBL4402603 | 0.79 | GPR6 (0.43) | F10GSK3BMCHR1 | |
| SCHEMBL1727490 | 0.78 | GSK3B (0.40) | MAPK14RAF1GSK3BMAPTGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586593-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | ACHE, C1R, C5 | KCNJ6 2700/4885KCNJ3 2350/4885MAPK14 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.