SCHEMBL4402747

SCHEMBL4402747

O=C1c2cccc(O)c2-c2cccc(O)c21

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.91
MAPT P10636 8/20 0.78
ALDH1A1 P00352 5/20 0.78
TDP1 Q9NUW8 5/20 0.78
MAPK1 P28482 4/20 0.78
HPGD P15428 4/20 0.78
ALOX15 P16050 4/20 0.78
HSD17B10 Q99714 4/20 0.78
TSHR P16473 3/20 0.78
SMN1; SMN2 Q16637 3/20 0.78
LMNA P02545 2/20 0.78
MAOB P27338 2/20 0.78
HTT P42858 1/20 0.78
STAT3 P40763 2/20 0.66
KMT2A Q03164 8/20 0.60
MEN1 O00255 7/20 0.60
KDM4E B2RXH2 6/20 0.59
RECQL P46063 6/20 0.59
POLB P06746 3/20 0.59
USP2 O75604 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthrarufin SCHEMBL29363946 0.95 MAOA (1.00) MAOAMAPTALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL29874705 0.95 MAOA (1.00) MAOAMAPTALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL187843 0.95 MAOA (1.00) MAOAMAPTALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL28419741 0.93 MAOA (0.95) MAOAMAPTALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL25355428 0.88 MAOA (0.86) MAOAMAPTALDH1A1TDP1MAPK1
1-Hydroxyanthraquinone SCHEMBL145303 0.88 MAOA (0.86) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL3198327 0.88 MAOA (0.86) MAOAMAPTALDH1A1TDP1MAPK1
1-Hydroxyanthraquinone SCHEMBL30912125 0.88 MAOA (0.86) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL30695844 0.88 MAOA (0.86) MAOAMAPTALDH1A1TDP1MAPK1
Danthron SCHEMBL29356886 0.88 MAPT (1.00) MAOAMAPTALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325697-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2014-05-14 EP disclosed
US-8703371-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-04-22 US disclosed
US-8703371-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-04-22 US disclosed
US-8512922-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-08-20 US disclosed
US-8512922-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-08-20 US disclosed
EP-2450747-B1 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KK (JP) 2013-07-17 EP disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-20120115076-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-05-10 US disclosed
US-20120115076-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-05-10 US disclosed
EP-2450747-A1 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2012-05-09 EP disclosed
EP-2325697-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2011-05-25 EP disclosed
US-20110117483-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-05-19 US disclosed
US-20110117483-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-05-19 US disclosed
EP-0906268-B1 ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS AVENTIS PHARMA INC (US) 2001-11-28 EP disclosed
US-6004959-A HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS HOECHST MARION ROUSSEL, INC. (US) 1999-12-21 US disclosed
EP-0906268-A1 ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS HOECHST MARION ROUSSEL, INC. (US) 1999-04-07 EP disclosed
WO-1997045397-A1 ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS HOECHST MARION ROUSSEL, INC. (US) 1997-12-04 WO disclosed