SCHEMBL4402947

SCHEMBL4402947

CCN(CC)c1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
PSMD14 O00487 1/20 0.50
CYP3A4 P08684 1/20 0.50
RECQL P46063 1/20 0.50
GFER P55789 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CNR2 P34972 12/20 0.47
ALDH3A1 P30838 1/20 0.47
ALDH1A3 P47895 1/20 0.47
CNR1 P21554 7/20 0.46
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
CYP2C19 P33261 1/20 0.44
S100B P04271 1/20 0.42
ACHE P22303 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161116 0.91 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL13778810 0.89 TSHR (0.41) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL13778811 0.89 TSHR (0.41) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL13778797 0.89 TSHR (0.41) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL13778816 0.89 TSHR (0.41) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL43704 0.89 ALDH1A1 (0.61) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL13778796 0.88 CNR2 (0.40) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL10025031 0.88 CNR2 (0.54) ALDH1A1TSHRMAPK1PSMD14CYP3A4
SCHEMBL21065779 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1PSMD14CYP3A4
Fluoride SCHEMBL11231084 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1PSMD14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed