Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.76 |
| ▸ | FGFR4 | P22455 | 12/20 | 0.76 |
| ▸ | FGFR2 | P21802 | 12/20 | 0.76 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886189 | 0.90 | FGFR1 (0.79) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20487744 | 0.90 | FGFR1 (0.79) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL4396227 | 0.90 | FGFR1 (0.62) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL5391527 | 0.90 | FGFR1 (0.71) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL28373856 | 0.87 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL28380121 | 0.87 | FGFR1 (0.60) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20487686 | 0.86 | FGFR1 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20487338 | 0.86 | FGFR1 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL4401627 | 0.86 | FGFR1 (0.66) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL28378571 | 0.86 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549651-B1 | PYRIMIDOPYRIMIDONES AS KINASE INHIBITORS | WARNER LAMBERT CO (US) | 2009-12-23 | — | — | EP | disclosed |