Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404806 | 0.89 | MEN1 (0.45) | CSNK2A1HIPK2MEN1KMT2AHPGD | |
| SCHEMBL29830673 | 0.84 | KDM4E (0.50) | CSNK2A1HIPK2HPGDKDM4EL3MBTL1 | |
| SCHEMBL2671852 | 0.84 | KDM4E (0.50) | CSNK2A1HIPK2HPGDKDM4EL3MBTL1 | |
| SCHEMBL31187507 | 0.82 | CSNK2A1 (0.47) | CSNK2A1HIPK2HPGDKDM4EL3MBTL1 | |
| SCHEMBL17142202 | 0.82 | CSNK2A1 (0.47) | CSNK2A1HIPK2HPGDKDM4EL3MBTL1 | |
| SCHEMBL4137619 | 0.80 | HIPK2 (0.45) | CSNK2A1HIPK2HPGDKDM4EL3MBTL1 | |
| SCHEMBL26928402 | 0.79 | HIPK2 (0.51) | HIPK2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL9883177 | 0.74 | ROCK1 (0.42) | MEN1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9860196 | 0.74 | SMN1; SMN2 (0.50) | MEN1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL30229317 | 0.73 | NNMT (0.48) | CSNK2A1HIPK2HPGDL3MBTL1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |