SCHEMBL440421

SCHEMBL440421

Clc1ccnc2c1ccc1c(Cl)ccnc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
ALDH1A1 P00352 5/20 0.50
TDP1 Q9NUW8 5/20 0.50
CCR1 P32246 4/20 0.50
CCR8 P51685 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CCR5 P51681 3/20 0.50
HSP90AA1 P07900 4/20 0.48
LMNA P02545 4/20 0.48
MAPT P10636 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
METAP2 P50579 2/20 0.48
METAP1 P53582 2/20 0.48
BRD4 O60885 1/20 0.48
HTT P42858 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
MMP14 P50281 3/20 0.47
CYP3A4 P08684 3/20 0.47
ALOX12 P18054 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503951 1.00 KDM4E (0.50) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL15255189 0.92 KDM4E (0.48) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL12564829 0.87 CCR1 (0.75) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL27876058 0.87 KDM4E (0.47) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL18283406 0.85 KDM4E (0.47) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL2372553 0.84 KDM4E (0.43) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL912543 0.83 CCR1 (0.65) KDM4EALDH1A1TDP1CCR1CCR8
Phenanthroline SCHEMBL10839118 0.83 CCR1 (0.65) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL30676376 0.82 KDM4E (0.46) KDM4EALDH1A1TDP1CCR1CCR8
SCHEMBL18984790 0.82 KDM4E (0.46) KDM4EALDH1A1TDP1CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
CN-118005700-A Synthesis and application of 8-hydroxyquinoline-N-oxide cobalt complex 玉林师范学院 2024-05-10 CN claimed
CN-117003774-A Preparation and application of 8-hydroxyquinoline-pyridine anticancer zinc (II) complex 玉林师范学院 2023-11-07 CN claimed
CN-116425804-B Cyclometalated iridium complex with anti-inflammatory and anti-tumor activities and preparation method and application thereof 东莞市人民医院 2023-09-29 CN claimed
CN-116789683-A 8-hydroxyquinoline anticancer zinc (II) complex and synthetic method and application thereof 玉林师范学院 2023-09-22 CN claimed
CN-116425804-A Cyclometalated iridium complex with anti-inflammatory and anti-tumor activities and preparation method and application thereof 东莞市人民医院 2023-07-14 CN claimed
CN-116239635-A 2-amino-8-hydroxyquinoline nickel complex for resisting drug-resistant ovarian cancer and preparation method thereof 玉林师范学院 2023-06-09 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-116082274-A 1,2, 3-oxathiazinane-2, 2-dioxide and synthesis method and application thereof 青岛科技大学 2023-05-09 CN claimed
CN-110845287-B Method for selective vulcanization of aliphatic amine 陕西师范大学 2023-02-14 CN claimed
EP-0894783-A1 Process for the synthesis of phenol from benzene Enichem S.p.A. (IT) 1999-02-03 EP claimed
US-5783164-A PALLADIUM CATALYST WITH A NITROGENATED LIGAND STABLE TO OXIDATION ENICHEM S.P.A. (IT) 1998-07-21 US claimed
EP-0853064-A1 Process for the synthesis of hydrogen peroxide ENICHEM S.p.A. (IT) 1998-07-15 EP claimed
US-5739264-A Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM S.P.A. (IT) 1998-04-14 US claimed
US-5734010-A Process for the preparation of copolymers of carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.P.A. (IT) 1998-03-31 US claimed
US-5717060-A Process for the preparation of copolymers based on carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.P.A. (IT) 1998-02-10 US claimed
EP-0808796-A1 Process for the preparation of hydrogen peroxide ENICHEM S.p.A. (IT) 1997-11-26 EP claimed
EP-0802213-A2 Process for the preparation of copolymers of carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.p.A. (IT) 1997-10-22 EP claimed
EP-0774479-A2 Process for the preparation of copolymers based on carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.p.A. (IT) 1997-05-21 EP claimed
EP-0728791-A1 Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM S.p.A. (IT) 1996-08-28 EP claimed