Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CCR1 | P32246 | 5/20 | 0.41 |
| ▸ | CCR8 | P51685 | 5/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MMP14 | P50281 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503951 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL440421 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL15255189 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL912543 | 0.78 | CCR1 (0.65) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Phenanthroline SCHEMBL10839118 | 0.78 | CCR1 (0.65) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL18283406 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23517029 | 0.74 | HSP90AA1 (0.41) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL30676376 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL18984790 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL12564829 | 0.72 | CCR1 (0.75) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9627632-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-04-18 | — | — | US | disclosed |
| EP-2550691-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20130009118-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-01-10 | — | — | US | disclosed |
| WO-2011116857-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |
| US-20060041159-A1 | Transition metal complexes with proton sponges as ligands | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2006-02-23 | — | — | US | disclosed |
| EP-1353931-B1 | TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2005-11-09 | — | — | EP | disclosed |
| EP-1353931-A1 | TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS | Studiengesellschaft Kohle mbH (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059134-A1 | TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130009118-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SOD1, L1CAM, EPCAM | KDM4E 3217/4885ALDH1A1 1742/4885TDP1 1991/4885 |
| US-20060041159-A1 | Transition metal complexes with proton sponges as ligands | HRH1, DCK, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KDM4E 1923/4885ALDH1A1 3322/4885TDP1 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.