Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.62 |
| ▸ | TMIGD3 | P0DMS9 | 5/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.51 |
| ▸ | CDK1 | P06493 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404463 | 0.87 | ADORA2A (0.61) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL987009 | 0.86 | ADORA2A (0.64) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL986631 | 0.85 | ADORA2A (0.63) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL987008 | 0.85 | ADORA2A (0.63) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL27772453 | 0.82 | ADORA2A (0.59) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL1146658 | 0.78 | ADORA2A (0.54) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL13870047 | 0.75 | CCNE1 (0.65) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL5162419 | 0.74 | ADORA2A (0.82) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL987753 | 0.73 | ADORA2A (0.62) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL5164692 | 0.73 | ADORA2A (0.74) | ADORA2AADORA1TMIGD3ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | disclosed |
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | BASILEA PHARMACEUTICA AG (CH) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | HRH4, HRH2, IL4 | ADORA2A 1843/4885ADORA1 789/4885TMIGD3 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.