Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18356669 | 1.00 | MGLL (0.42) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL17721385 | 0.91 | MGLL (0.43) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL26412334 | 0.88 | MGLL (0.40) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL10018583 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL29441383 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL24621693 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL29869032 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL29869052 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL29608026 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 | |
| SCHEMBL30259429 | 0.87 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156778-B2 | Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-10-13 | — | — | US | disclosed |
| US-20120322053-A1 | CROSS-COUPLED PEPTIDE NUCLEIC ACIDS FOR DETECTION OF NUCLEIC ACIDS OF PATHOGENS | APPELLA DANIEL H (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120107794-A1 | Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2012-05-03 | — | — | US | disclosed |