SCHEMBL4405423

SCHEMBL4405423

CCNC(=O)N(CC)C(=O)NCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
GAA P10253 1/20 0.48
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
KMT2A Q03164 1/20 0.37
MCL1 Q07820 1/20 0.36
CYP3A4 P08684 1/20 0.35
FAAH O00519 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRL1 P41146 1/20 0.34
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
HTT P42858 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10068166 0.87 ALDH1A1 (0.44) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL6682335 0.87 ALDH1A1 (0.44) ALDH1A1GAAMMP1MMP2MMP3
Hydrochloric Acid SCHEMBL11687442 0.85 ALDH1A1 (0.42) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL12016262 0.85 ALDH1A1 (0.42) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL11687438 0.85 ALDH1A1 (0.42) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL10106480 0.84 ALDH1A1 (0.41) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL14817327 0.84 ALDH1A1 (0.41) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL27426652 0.84 ALDH1A1 (0.41) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL3079605 0.82 ALDH1A1 (0.40) ALDH1A1GAAMMP1MMP2MMP3
SCHEMBL4403350 0.80 ALDH1A1 (0.43) ALDH1A1GAAMMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404348-B2 Resilient, water dispersible polyurethane foams and products incorporating same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2013-03-26 US disclosed
US-20120219780-A1 Resilient, Water Dispersible Polyurethane Foams and Products Incorporating Same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2012-08-30 US disclosed
US-8173718-B2 Resilient, water dispersible polyurethane foams and products incorporating same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2012-05-08 US disclosed
US-8173718-B2 Resilient, water dispersible polyurethane foams and products incorporating same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2012-05-08 US disclosed
US-20090075030-A1 Resilient, Water Dispersible Polyurethane Foams and Products Incorporating Same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2009-03-19 US disclosed
US-20090075030-A1 Resilient, Water Dispersible Polyurethane Foams and Products Incorporating Same GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2009-03-19 US disclosed