SCHEMBL4405477

SCHEMBL4405477

Cc1nnnn1C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410900 0.75
SCHEMBL4410890 0.75 NOTUM (0.35) GAARAB9ANOTUM
SCHEMBL4416160 0.72
SCHEMBL4406031 0.71 NOTUM (0.33) NOTUM
SCHEMBL4410972 0.71 ALDH1A1 (0.35) ALDH1A1HSP90AA1MAPTHPGDHTT
SCHEMBL4404301 0.71 ALDH1A1 (0.33) ALDH1A1HSP90AA1MAPTHPGDHTT
SCHEMBL4409255 0.70 ALDH1A1 (0.35) ALDH1A1HSP90AA1MAPTHPGDHTT
SCHEMBL4405708 0.70
SCHEMBL4414836 0.70
SCHEMBL4403688 0.70 ALDH1A1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed