SCHEMBL440563

SCHEMBL440563

NC(=O)NCCC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114363 1.00 ECE1 (0.50)
SCHEMBL2035521 0.84 PRMT1 (0.54)
SCHEMBL2172441 0.82 PRMT1 (0.64)
Beta-Alanine SCHEMBL17165678 0.82 ADRA1A (0.48)
Pyrimidine SCHEMBL20898596 0.82 RECQL (0.41)
SCHEMBL9307514 0.80 PRMT1 (0.68)
SCHEMBL11039434 0.80 PRMT1 (0.68)
SCHEMBL2028710 0.80 PRMT1 (0.68)
SCHEMBL1326707 0.80
Ompenaclid SCHEMBL33761 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 978 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-4692783-A1 BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF Shanghai Ganning Medical and Technology Co., Ltd (CN) 2026-02-11 EP claimed
US-20250341515-A1 METABOLOMIC BIOMARKERS FOR ACUTE KIDNEY INJURY, ASSAYS, COMPOSITIONS AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-11-06 US claimed
EP-4587116-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2025-07-23 EP claimed
US-12292445-B2 Methods of selecting subjects for treatment with metabolomic modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-06 US claimed
WO-2025054048-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING LIPID AND CHOLESTEROL METABOLISM ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2025-03-13 WO claimed
CN-119555822-A Urine metabolism marker composition for diagnosis of cancer seeds of pan-cancer, screening method and application 哈尔滨脉图精准技术有限公司 2025-03-04 CN claimed
CN-119510604-A Biomarker for predicting whether ACLF patient will die, system and application thereof 上海甘宁医疗科技有限公司 2025-02-25 CN claimed
US-20020132283-A1 Composition for determining pyrimidine metabolizing activity OTSUKA PHARMACEUTICAL CO. LTD. (JP) 2002-09-19 US claimed
US-20020039990-A1 Gene sequence variances in genes related to folate metabolism having utility in determining the treatment of disease VARIAGENICS, INC. 2002-04-04 US claimed
EP-1142995-A1 ANTIURACIL MONOCLONAL ANTIBODY TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2001-10-10 EP claimed
EP-0628637-B1 PROCESS FOR PRODUCING D-ALPHA-AMINO ACIDS KANEGAFUCHI CHEMICAL IND (JP) 2001-06-13 EP claimed
EP-1100964-A1 GENE SEQUENCE VARIANCES WITH UTILITY IN DETERMINING THE TREATMENT OF DISEASE Variagenics, Inc. (US) 2001-05-23 EP claimed
CN-1282329-A I (ortho)-anthranilamide derivatives as anti-coagulants SCHERING AG (DE) 2001-01-31 CN claimed
WO-2000004194-A1 GENE SEQUENCE VARIANCES WITH UTILITY IN DETERMINING THE TREATMENT OF DISEASE VARIAGENICS, INC. (US) 2000-01-27 WO claimed
US-5902736-A USING DECARBAMYLASE FROM COMAMONAS, ALCALIGENES, RHIZOBIUM, BLASTOBACTER, SPOROSARCINA, AND BRADYRHYZOBIUM SPECIES IN AQUEOUS MEDIUM; AS CHEMICAL INTERMEDIATES FOR SEMISYNTHETIC PENICILLIN AND CEPHALOSPORIN KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-05-11 US claimed
EP-0628637-A1 PROCESS FOR PRODUCING D-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1994-12-14 EP claimed
EP-0173276-A2 Method for the determination of substrate or enzyme activity KYOWA HAKKO KOGYO CO., LTD. (JP) 1986-03-05 EP claimed