Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985918 | 0.84 | KCNN4 (0.39) | KCNN4MAPK1MAP4K4ACHE | |
| SCHEMBL985013 | 0.83 | LRRK2 (0.42) | KCNN4MET | |
| SCHEMBL985352 | 0.82 | SLC2A1 (0.41) | MAP4K4 | |
| SCHEMBL986663 | 0.82 | LRRK2 (0.42) | KCNN4ACHE | |
| SCHEMBL985829 | 0.81 | LRRK2 (0.44) | KCNN4MET | |
| SCHEMBL987392 | 0.81 | KCNN4 (0.37) | KCNN4ACHE | |
| SCHEMBL986434 | 0.81 | KCNN4 (0.37) | KCNN4ACHE | |
| SCHEMBL985789 | 0.81 | KCNN4 (0.37) | KCNN4ACHE | |
| SCHEMBL983613 | 0.81 | MEN1 (0.38) | KCNN4MAPK1METMAP4K4 | |
| SCHEMBL4405584 | 0.81 | KCNN4 (0.38) | KCNN4MAPK1MAP4K4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004625-B1 | C-MET PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | VERTEX PHARMA (US) | 2009-12-30 | — | — | EP | claimed |