Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660440 | 1.00 | HPGD (0.38) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL2361897 | 0.90 | HPGD (0.32) | HPGDTSHRPLA2G7 | |
| SCHEMBL662188 | 0.83 | PLA2G7 (0.42) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL661630 | 0.82 | TYMP (0.38) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL662247 | 0.81 | TSHR (0.38) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL20556066 | 0.80 | PLA2G7 (0.32) | PLA2G7 | |
| Plosaracetam SCHEMBL24390914 | 0.79 | HPGD (0.35) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| Plosaracetam SCHEMBL16431938 | 0.79 | HPGD (0.35) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL660197 | 0.79 | HPGD (0.38) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL663012 | 0.77 | HPGD (0.35) | HPGDTSHRPLA2G7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |