Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405606 | 0.87 | DGAT1 (0.52) | DGAT1NPC1RAB9AALDH1A1 | |
| SCHEMBL4299277 | 0.85 | DGAT1 (0.73) | DGAT1GLAL3MBTL1NPC1RAB9A | |
| SCHEMBL4291949 | 0.83 | DGAT1 (0.71) | DGAT1NPC1RAB9AALDH1A1 | |
| SCHEMBL4294211 | 0.83 | DGAT1 (0.71) | DGAT1NPC1RAB9AALDH1A1 | |
| SCHEMBL4291993 | 0.81 | DGAT1 (0.73) | DGAT1GLAL3MBTL1NPC1RAB9A | |
| SCHEMBL4296708 | 0.80 | DGAT1 (1.00) | DGAT1NPC1RAB9A | |
| SCHEMBL4296776 | 0.78 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL4296728 | 0.78 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL4300794 | 0.77 | DGAT1 (0.73) | DGAT1NPC1RAB9AALDH1A1 | |
| SCHEMBL4297575 | 0.76 | DGAT1 (0.82) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |