Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408228 | 0.95 | SLC9A1 (0.39) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL4409207 | 0.93 | SLC9A1 (0.41) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL4409406 | 0.89 | CYP1A2 (0.41) | KMT2AMEN1SLC9A1CYP2C19LMNA | |
| SCHEMBL4411123 | 0.80 | — | — | |
| SCHEMBL18496466 | 0.72 | CYP1A2 (0.57) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL2091620 | 0.72 | KMT2A (0.47) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL4406977 | 0.72 | MAPT (0.42) | KMT2ALMNAALDH1A1MAPTGRM2 | |
| SCHEMBL11767211 | 0.71 | KMT2A (0.43) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL5154397 | 0.71 | HTT (0.45) | KMT2AMEN1HTTSLC9A1CYP2C19 | |
| SCHEMBL4414845 | 0.71 | KMT2A (0.45) | KMT2AMEN1HTTSLC9A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |