SCHEMBL4407269

SCHEMBL4407269

Cn1nnnc1C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.35
CACNA1B Q00975 2/20 0.35
APBA1 Q02410 2/20 0.35
HSP90AA1 P07900 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CCR6 P51684 1/20 0.33
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407091 0.81 ALDH1A1 (0.37) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4408448 0.74 ALDH1A1 (0.34) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4411129 0.74 ALDH1A1 (0.35) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4408846 0.74 CYP1A2 (0.42) ALDH1A1HPGD
SCHEMBL4414839 0.73 ALDH1A1 (0.33) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4402500 0.73 ALDH1A1 (0.33) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4404301 0.73 ALDH1A1 (0.33) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4408134 0.72 ALDH1A1 (0.41) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4416627 0.72 CYP1A2 (0.40) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4411090 0.71 KMT2A (0.38) ALDH1A1MAPTHTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed