SCHEMBL4407300

SCHEMBL4407300

Nc1c(O)ccc(C23CC4CC(C2)CC(c2ccc(O)c(N)c2Oc2ccccc2)(C4)C3)c1Oc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
EPHX2 P34913 2/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
RARB P10826 3/20 0.32
RARA P10276 2/20 0.32
RARG P13631 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410696 0.85 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4418788 0.81 KDM1A (0.33) KMT2AMEN1EPHX2POLBKDM4E
SCHEMBL4583509 0.76 KMT2A (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2708789 0.75 KMT2A (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2706967 0.74 ESR1 (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2747046 0.74 KDM4E (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4408351 0.74 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12339883 0.74 KMT2A (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13004821 0.70 IDO1 (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2706958 0.70 ALDH1A1 (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed