Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 10/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12710364 | 0.89 | GPBAR1 (0.42) | GPBAR1MEN1KMT2ARORCRAB9A | |
| SCHEMBL21569309 | 0.88 | GPBAR1 (0.39) | GPBAR1MEN1KMT2ARORCRAB9A | |
| SCHEMBL13726383 | 0.88 | GPBAR1 (0.40) | GPBAR1MEN1KMT2ARORCRAB9A | |
| SCHEMBL21359674 | 0.86 | GPBAR1 (0.38) | GPBAR1MEN1KMT2ARORCRAB9A | |
| SCHEMBL12710323 | 0.82 | GPBAR1 (0.43) | GPBAR1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12710331 | 0.82 | MEN1 (0.44) | GPBAR1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12710355 | 0.82 | NOS3 (0.46) | GPBAR1MEN1KMT2A | |
| SCHEMBL12710343 | 0.80 | GPBAR1 (0.40) | GPBAR1MEN1KMT2AMAPT | |
| SCHEMBL12710341 | 0.80 | GPBAR1 (0.41) | GPBAR1MEN1KMT2ARORCRAB9A | |
| SCHEMBL12710321 | 0.80 | GPBAR1 (0.42) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-9695126-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | US | disclosed |
| US-9398767-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-26 | — | — | US | disclosed |
| EP-3000809-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2430000-B1 | Fungicide pyrazole carboxamide derivates | BAYER IP GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-8772266-B2 | Fungicide pyrazole carboxamides derivates | BAYER CROPSCIENCE AG (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG | 2014-05-29 | — | — | US | disclosed |
| CN-102421757-A | Fungicide pyrazole carboxamide derivatives | BAYER CROPSCIENCE AG | 2012-04-18 | — | — | CN | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20110082036-A1 | Active Compound Combinations Comprising Arylamidines and N-Cycloalkylamides | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20110082036-A1 | Active Compound Combinations Comprising Arylamidines and N-Cycloalkylamides | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| EP-2251331-A1 | Fungicide pyrazole carboxamides derivatives | Bayer CropScience AG (DE) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | GPBAR1 4515/4885MEN1 2227/4885KMT2A 1882/4885 |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | GPBAR1 4515/4885MEN1 2227/4885KMT2A 1882/4885 |
| US-20110082036-A1 | Active Compound Combinations Comprising Arylamidines and N-Cycloalkylamides | NAT1, NACA, AADAC | GPBAR1 4255/4885MEN1 3749/4885KMT2A 1258/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | GPBAR1 4675/4885MEN1 1717/4885KMT2A 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.