Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485771 | 0.82 | GRIA1 (0.52) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL615017 | 0.82 | GRIA1 (0.52) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL939749 | 0.82 | GRIA1 (0.52) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL6255381 | 0.77 | GRIA1 (0.48) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL4757741 | 0.77 | GRIA1 (0.48) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL20821107 | 0.76 | SMN1; SMN2 (0.39) | GRIA1GRIA4GRIK5GRIA3SMN1; SMN2 | |
| SCHEMBL5298700 | 0.76 | GRIA1 (0.47) | GRIA1GRIA4GRIK5GRIA3GRIK1 | |
| SCHEMBL1342487 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2NPSR1KMT2ATAAR1MAPK1 | |
| SCHEMBL9623345 | 0.74 | HPGD (0.46) | SMN1; SMN2NPSR1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL5324248 | 0.71 | GRM2 (0.41) | GRIA1GRIA4GRIK5GRIA3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090180958-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD. (FI) | 2009-07-16 | — | — | US | disclosed |
| EP-1874800-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | Karyon-CTT Ltd (FI) | 2008-01-09 | — | — | EP | disclosed |
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
| WO-2006114478-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090180958-A1 | Diagnostic and therapeutic agents | TPX2, ZFX, ZYX | GRIA1 1388/4885GRIA4 2621/4885GRIK5 1238/4885 |
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | GRIA1 3993/4885GRIA4 4357/4885GRIK5 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.