SCHEMBL4407700

SCHEMBL4407700

CCO[Si](CCCN(CCC[Si](OCC)(OCC)OCC)C(=O)NCCCCCCNC(=O)N(CCC[Si](OCC)(OCC)OCC)CCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.36
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX2 P34913 2/20 0.33
CASP2 P42575 1/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25768096 0.97 EPHX1 (0.34) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL2563904 0.95 CA12 (0.32) EPHX1CA12CA1CA2CA9
SCHEMBL4534944 0.94 EPHX1 (0.42) EPHX1EPHX2CASP2FAAH
SCHEMBL14672658 0.94 EPHX1 (0.42) EPHX1EPHX2CASP2FAAH
SCHEMBL23373135 0.91 EPHX1 (0.42) EPHX1EPHX2CASP2FAAH
SCHEMBL1203085 0.89 EPHX1 (0.40) EPHX1EPHX2CASP2FAAH
SCHEMBL13934745 0.89 EPHX1 (0.40) EPHX1EPHX2CASP2FAAH
SCHEMBL29837984 0.89 EPHX1 (0.40) EPHX1EPHX2CASP2FAAH
SCHEMBL21924930 0.89 EPHX1 (0.30) EPHX1
SCHEMBL21924986 0.88 EPHX1 (0.35) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS SUMO1, CAD, UFM1 EPHX1 4148/4885KDM4E 732/4885MAPK1 1743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.