Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 3/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407731 | 1.00 | DPP8 (0.38) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL4407708 | 0.86 | DPP8 (0.37) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL8239022 | 0.86 | DPP8 (0.37) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL8060885 | 0.84 | XIAP (0.36) | DPP8DPP4DPP9DPP7XIAP | |
| SCHEMBL8241586 | 0.81 | ELANE (0.40) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL4407737 | 0.81 | ELANE (0.40) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL13594519 | 0.79 | DPP8 (0.37) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL4458000 | 0.79 | DPP8 (0.37) | DPP8DPP4DPP9DPP7ELANE | |
| SCHEMBL4595406 | 0.77 | DPP8 (0.35) | DPP8DPP9DPP7ACEAGTR2 | |
| SCHEMBL8200153 | 0.77 | DPP8 (0.35) | DPP8DPP9DPP7ACEAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |