Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187686 | 0.87 | DPP8 (0.35) | DPP8DPP9DPP7ABHD6DDB1 | |
| SCHEMBL4406308 | 0.85 | DPP4 (0.44) | DPP8DPP9DPP7ABHD6DPP4 | |
| SCHEMBL4257147 | 0.85 | DPP4 (0.44) | DPP8DPP9DPP7ABHD6DPP4 | |
| SCHEMBL4407736 | 0.84 | DPP8 (0.38) | XIAPDPP8DPP9DPP7BIRC3 | |
| SCHEMBL4407731 | 0.84 | DPP8 (0.38) | XIAPDPP8DPP9DPP7BIRC3 | |
| SCHEMBL4253457 | 0.83 | XIAP (0.33) | XIAPBIRC3 | |
| SCHEMBL4253455 | 0.83 | XIAP (0.33) | XIAPBIRC3 | |
| SCHEMBL8236830 | 0.82 | ELANE (0.36) | XIAPDPP8DPP9DPP7DDB1 | |
| SCHEMBL4259244 | 0.82 | ELANE (0.37) | — | |
| SCHEMBL8241586 | 0.80 | ELANE (0.40) | DPP8DPP9DPP7DPP4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |