Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410762 | 0.98 | MIF (0.33) | ALDH1A1KCNH2CYP19A1GABRA2GABRB2 | |
| SCHEMBL4405651 | 0.93 | GABRA2 (0.30) | ALDH1A1GABRA2GABRB2 | |
| SCHEMBL4403753 | 0.87 | GGPS1 (0.33) | ALDH1A1CYP19A1GABRA2GABRB2MIF | |
| SCHEMBL4407835 | 0.85 | — | — | |
| SCHEMBL4407375 | 0.85 | GGPS1 (0.32) | CYP19A1GABRA2GABRB2MIFNPC1 | |
| SCHEMBL4407156 | 0.84 | MIF (0.33) | ALDH1A1KCNH2CYP19A1MIFXDH | |
| SCHEMBL4408964 | 0.83 | GABRA2 (0.35) | ALDH1A1CYP19A1GABRA2GABRB2MIF | |
| SCHEMBL4405497 | 0.82 | MIF (0.33) | ALDH1A1MIFXDH | |
| SCHEMBL4409256 | 0.81 | GABRA2 (0.34) | GABRA2GABRB2MIF | |
| SCHEMBL4411186 | 0.80 | GABRA2 (0.34) | CYP19A1GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |