SCHEMBL4407971

SCHEMBL4407971

CC(C)CC=CC=CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.46
ACHE P22303 1/20 0.40
BACE1 P56817 1/20 0.40
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38
GABRG3 Q99928 2/20 0.38
GABRQ Q9UN88 2/20 0.38
CNR2 P34972 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407967 1.00 PPARA (0.46) PPARAACHEBACE1GABRPGABRD
SCHEMBL6866865 1.00 PPARA (0.46) PPARAACHEBACE1GABRPGABRD
SCHEMBL5568055 1.00 PPARA (0.46) PPARAACHEBACE1GABRPGABRD
SCHEMBL13604722 0.84 CNR2 (0.38) PPARACNR2CNR1PPARGPPARD
SCHEMBL12973059 0.83
SCHEMBL15353 0.83
SCHEMBL15352 0.83
SCHEMBL17866776 0.83 PPARA (0.43) PPARAACHEBACE1GABRPGABRD
SCHEMBL9446902 0.83 PPARA (0.43) PPARAACHEBACE1GABRPGABRD
SCHEMBL17866774 0.83 PPARA (0.43) PPARAACHEBACE1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-108699098-B C-glucoside derivative having fused benzene ring or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition comprising same 第一药品株式会社 2022-01-25 CN disclosed
US-10752604-B2 C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same Je II Pharmaceutical Co., Ltd. (KR) 2020-08-25 US disclosed
EP-3404033-B1 C-GLUCOSIDE DERIVATIVE CONTAINING FUSED PHENYL RING OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME JEIL PHARMACEUTICAL CO LTD (KR) 2020-08-05 EP disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20190002425-A1 C-Glucoside Derivative Containing Fused Phenyl Ring or Pharmaceutically Acceptable Salt Thereof, Process for Preparing Same, and Pharmaceutical Composition Comprising Same JE IL PHARMACEUTICAL CO., LTD. (KR) 2019-01-03 US disclosed
EP-3404033-A1 C-GLUCOSIDE DERIVATIVE CONTAINING FUSED PHENYL RING OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Jeil Pharmaceutical Co., Ltd. (KR) 2018-11-21 EP disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20050287641-A1 Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase ECOPIA BIOSCIENCES, INC. 2005-12-29 US disclosed
US-20050106691-A1 Process for the production of ramoplanin-like amide derivatives VICURON PHARMACEUTICALS INC. (US) 2005-05-19 US disclosed
EP-1326983-B1 GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS ECOPIA BIOSCIENCES INC (CA) 2005-04-06 EP disclosed
WO-2005010117-A1 CLING ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-02-03 WO disclosed
US-20050000642-A1 Cling articles 3M INNOVATIVE PROPERTIES COMPANY 2005-01-06 US disclosed
EP-1483286-A1 A PROCESS FOR THE PRODUCTION OF RAMOPLANIN-LIKE AMIDE DERIVATIVES Vicuron Pharmaceuticals, Inc. (US) 2004-12-08 EP disclosed
WO-2003076460-A1 A PROCESS FOR THE PRODUCTION OF RAMOPLANIN-LIKE AMIDE DERIVATIVES VICURON PHARMACEUTICALS INC. (US) 2003-09-18 WO disclosed
EP-1326983-A2 GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS Ecopia Biosciences Inc. (CA) 2003-07-16 EP disclosed
US-20020164747-A1 Gene cluster for ramoplanin biosynthesis ECOPIA BIOSCIENCES INC. 2002-11-07 US disclosed
WO-2002031155-A2 GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS ECOPIA BIOSCIENCES INC. (CA) 2002-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190002425-A1 C-Glucoside Derivative Containing Fused Phenyl Ring or Pharmaceutically Acceptable Salt Thereof, Process for Preparing Same, and Pharmaceutical Composition Comprising Same SLC5A2, SLC5A1, UGGT1 PPARA 615/4885ACHE 3857/4885BACE1 3374/4885
US-10752604-B2 C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same SLC5A2, SLC5A1, UGGT1 PPARA 615/4885ACHE 3857/4885BACE1 3374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.