Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514608 | 0.86 | KDM4E (0.50) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL26597 | 0.85 | KDM4E (0.57) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL7790779 | 0.84 | KDM4E (0.43) | KDM4EGPR3PDPK1CYP1A2MAPT | |
| SCHEMBL12474840 | 0.80 | KDM4E (0.46) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL27857583 | 0.78 | KDM4E (0.39) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL1395938 | 0.76 | KDM4E (0.50) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL15578380 | 0.76 | KDM4E (0.50) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL17511855 | 0.75 | KDM4E (0.42) | KDM4EGPR3CYP1A2NPC1SMN1; SMN2 | |
| SCHEMBL28260376 | 0.75 | KDM4E (0.45) | KDM4EGPR3PDPK1CYP1A2NPC1 | |
| SCHEMBL2514753 | 0.74 | CYP3A4 (0.53) | KDM4EGPR3CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 50510 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238264-A1 | INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF | DISARM THERAPEUTICS, INC. | 2024-07-18 | — | — | US | claimed |
| CN-110400884-B | Organic light emitting device and method of manufacturing the same | 三星显示有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118324788-A | Organic electroluminescent compound and application thereof | 宁波卢米蓝新材料有限公司 | 2024-07-12 | — | — | CN | claimed |
| WO-2024140638-A1 | COMPOUND BASED ON SULFUR/OXYGEN SUBSTITUTED GLUTARIMIDE-BASED ISOINDOLINONE SKELETON AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-07-04 | — | — | WO | claimed |
| CN-109994638-B | Organic light emitting device and electronic device | 三星显示有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118255717-A | Dihydroacenaphthenyl derivative organic luminescent material, preparation method and electroluminescent device | 成都维拓立柔性电子技术有限公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| CN-118239966-A | Organic electroluminescent compound and application thereof | 宁波卢米蓝新材料有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118239898-A | Blue light material, preparation method and organic electroluminescent device | 成都维拓立柔性电子技术有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-110277500-B | Organic light emitting device | 三星显示有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-0271144-A2 | Process for the carbonylation of acetylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | claimed |
| CN-87107279-A | Process for the carbonylation of acetylenically unsaturated compounds | — | 1988-06-15 | — | — | CN | claimed |
| US-4725596-A | Pyrimidine derivatives having anti-allergy, anti-inflammatory and immuno suppressant activity | SCHERING CORPORATION (US) | 1988-02-16 | — | — | US | claimed |
| EP-0229823-A1 | POLYCYCLIC QUINOLINE, NAPHTHYRIDINE AND PYRAZINOPYRIDINE DERIVATIVES. | SCHERING CORP (US) | 1987-07-29 | — | — | EP | claimed |
| EP-0220282-A1 | PYRIMIDINE DERIVATIVES HAVING ANTI-ALLERGY, ANTI-INFLAMMATORY AND IMMUNO SUPPRESSANT ACTIVITY | SCHERING CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| US-4652564-A | Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents | SCHERING CORPORATION (US) | 1987-03-24 | — | — | US | claimed |
| WO-1986007359-A2 | POLYCYCLIC QUINOLINE, NAPHTHYRIDINE AND PYRAZINOPYRIDINE DERIVATIVES | SCHERING CORPORATION (US) | 1986-12-18 | — | — | WO | claimed |
| WO-1986006375-A2 | PYRIMIDINE DERIVATIVES HAVING ANTI-ALLERGY, ANTI-INFLAMMATORY AND IMMUNO SUPPRESSANT ACTIVITY | SCHERING CORPORATION (US) | 1986-11-06 | — | — | WO | claimed |
| US-4188274-A | DECARBOXYLATION | STANDARD OIL COMPANY (INDIANA) (US) | 1980-02-12 | — | — | US | claimed |
| US-4174447-A | SILVER SALTS OF CARBOXY ACIDS | STANDARD OIL COMPANY (INDIANA) (US) | 1979-11-13 | — | — | US | claimed |